Increased soluble P-selectin levels following deep venous thrombosis: cause or effect?
نویسندگان
چکیده
منابع مشابه
Increased levels of soluble P-selectin in hypercholesterolemic patients.
BACKGROUND Hypercholesterolemia is considered a major risk factor for the development of atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be observed in vivo in hypercholesterolemic patients and may have pathophysiological implications in the occurrence of cardiovascular events. P-selectin may play an important role in the pathogenesis of multicellular events,...
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Introduction: Psoriasis is an inflammatory skin disease in which abnormal individual immune reactivity plays an important role. Eselectin and P-selectin are adhesion molecules expressed on vascular endothelial cells in several inflammatory skin diseases, including psoriasis. The aim of the present study was to describe selected immunological changes, concerning adhesion molecules status (sEsele...
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Leukocyte adhesion, transendothelial migration, and stasis are important components in the pathogenesis of deep vein thrombosis. Anesthetized cats were treated with saline, a recombinant soluble form of P-selectin glycoprotein ligand-1 (rPSGL-Ig), or an E- and L-selectin antibody (EL-246) before exposure and occlusion of a jugular vein. After 2 or 6 hours of occlusion, jugular veins were perfus...
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To the Editor: We would like to bring to your attention and to the attention of the scientific community that unilateral lower limb suspension (ULLS), a model for physical inactivity and simulating microgravity unloading in humans, is associated with an increased risk of deep venous thrombosis (DVT). In the ULLS model, which was originally developed by Berg et al. (2), subjects use crutches for...
متن کاملIncreased levels of soluble adhesion molecules, E-selectin and P-selectin, in patients with infective endocarditis and embolic events.
AIMS Inflammation-induced procoagulant changes and endothelial cell activation appear to play an important role in thromboembolic complications of infective endocarditis. Hence, the aim of this study was to compare the plasma levels of soluble adhesion molecules E- and P-selectin in infective endocarditis patients with and without embolic events, and healthy subjects. METHODS AND RESULTS The ...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2000
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2000.01813.x